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I Am Looking For Information Regarding Simponi Aria Infusion Treatment - Pros, Cons, Successes, Failures. I Am Reluctant To Try. Thanks!

A MyPsoriasisTeam Member asked a question 💭
Seattle, WA
January 16, 2024
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A MyPsoriasisTeam Member

Certainly! Here is detailed information about Simponi Aria (Golimumab) for psoriasis based on the knowledge base:

Simponi Aria (Golimumab) Overview
- Approval: Approved by the U.S. Food and Drug Administration (FDA) to treat adults and children over age 2 with active psoriatic arthritis
- Type: Biologic disease-modifying Show Full Answer

Certainly! Here is detailed information about Simponi Aria (Golimumab) for psoriasis based on the knowledge base:

Simponi Aria (Golimumab) Overview
- Approval: Approved by the U.S. Food and Drug Administration (FDA) to treat adults and children over age 2 with active psoriatic arthritis.
- Type: Biologic disease-modifying antirheumatic drug (DMARD).
- Mechanism: Works by inhibiting tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks.

Administration
- Method: Administered as an intravenous infusion.
- Frequency: Every eight weeks after initial loading doses.

Pros
- Effectiveness: Targets and neutralizes specific immune system components involved in psoriasis.
- Convenience: Administered every eight weeks, which may be more convenient than more frequent treatments.

Cons
- Common Side Effects:
- Upper respiratory tract infection
- Increased liver enzymes
- Viral infection
- Decreased blood cell count
- Bronchitis
- Hypertension
- Rash

- Rare but Serious Side Effects:
- Severe infections
- Congestive heart failure
- Hepatitis B reinfection
- Increased risk for lymphoma
- Demyelinating disorders such as multiple sclerosis
- Lupus-like syndrome
- Hypersensitivity reactions

Considerations
- Risks: The potential for serious side effects should be weighed against the benefits.
- Monitoring: Regular monitoring by a healthcare provider is essential to manage and mitigate risks.

For more details, you can visit the official site: [SimponiAria.com](https://www.simponiaria.com/psoriatic-arthritis/).

If you have any more specific questions or concerns, it's always best to discuss them with your healthcare provider.

July 14, 2024
A MyPsoriasisTeam Member

I have never done infusions they seem quite invasive . I have tried simponi and had a bad reaction with the injections - made me worse

January 17, 2024
A MyPsoriasisTeam Member

Yikes! Thanks for sharing, am so sorry thst had you had these complications. Did u try other biologics? How is your current treatment plan working?

January 16, 2024
A MyPsoriasisTeam Member

I had two infusions and got double pneumonia and strep. Killed my immune system. Haven’t done any treatment except back epidurals shoulders and wrist and hip cortisone.

January 16, 2024

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