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Been On Combination Therapy, Otezla/Humira >10 Yrs. New Insur.now Denying It. Dr. Switching To Skyrizi Alone. Thoughts?

A MyPsoriasisTeam Member asked a question 💭
Youngstown, OH

I have Psoriatic Arthritis and I'm worried that switching from combination thereapy - Otezla/ Humira to Skyrizi alone will cause my psoriasis to flare up bad. has anyone else gone through this? I had United health care before and no issues, now Med mutual of Ohio is putting me through hell

https://insur.now
https://insur.now
February 2, 2024
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A MyPsoriasisTeam Member

Well, after stopping Otezla for Skyrizi alone, I couldn't walk without severe pain, I was diagnosed with PTTD. Then by June of 2024 the psoriasis on my scalp came back after 14 years of being clear. So after many exhaustive phone calls, letters, preauths, denials, appeals, denials - by October my Otezla was approved. within a month the psoriasis disappeared and by January I can finally walk without assistance and without pain. Now, this year- new insurance carrier, and they are once again denying the Otezla. so no, skyrizi alone did NOT help.

February 17
MyPsoriasisTeam

Switching to Skyrizi (risankizumab-rzaa) alone could be a viable option for managing your psoriatic arthritis (PsA) and psoriasis. Here are some key points about Skyrizi based on the knowledge base:

- Mechanism of Action: Skyrizi is a biologic therapy that targets IL-23, a protein involved in inflammation, helping to Show Full Answer

Switching to Skyrizi (risankizumab-rzaa) alone could be a viable option for managing your psoriatic arthritis (PsA) and psoriasis. Here are some key points about Skyrizi based on the knowledge base:

- Mechanism of Action: Skyrizi is a biologic therapy that targets IL-23, a protein involved in inflammation, helping to reduce joint pain, stiffness, and swelling.
- Administration: It is administered as a subcutaneous injection every 12 weeks after initial loading doses.
- Efficacy: Clinical trials (KEEPSAKE 1 and 2) showed significant improvement in PsA symptoms, with over half of participants experiencing reduced inflammation and swelling.
- Side Effects: Potential side effects include serious allergic reactions and an increased risk of infections.

Always discuss with your doctor to ensure this switch aligns with your specific health needs.

July 31, 2024

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