Connect with others who understand.

Sign up Log in
Quick Links
all articles Q&A Treatments A-Z Help Center Guidelines Crisis Accessibility
Resources
Emotional Well-Being Living with Psoriasis Psoriasis Condition Information Psoriasis Symptoms Psoriasis Treatments Psoriatic Arthritis News Videos All Resources
About MyPsoriasisTeam
What is This Site Terms of Use Privacy policy
Powered By
Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Been On Combination Therapy, Otezla/Humira >10 Yrs. New Insur.now Denying It. Dr. Switching To Skyrizi Alone. Thoughts?

A MyPsoriasisTeam Member asked a question 💭
Youngstown, OH

I have Psoriatic Arthritis and I'm worried that switching from combination thereapy - Otezla/ Humira to Skyrizi alone will cause my psoriasis to flare up bad. has anyone else gone through this? I had United health care before and no issues, now Med mutual of Ohio is putting me through hell

https://insur.now
https://insur.now
February 2, 2024
•
View reactions
A MyPsoriasisTeam Member

Well, after stopping Otezla for Skyrizi alone, I couldn't walk without severe pain, I was diagnosed with PTTD. Then by June of 2024 the psoriasis on my scalp came back after 14 years of being clear. So after many exhaustive phone calls, letters, preauths, denials, appeals, denials - by October my Otezla was approved. within a month the psoriasis disappeared and by January I can finally walk without assistance and without pain. Now, this year- new insurance carrier, and they are once again denying the Otezla. so no, skyrizi alone did NOT help.

February 17
MyPsoriasisTeam

Switching to Skyrizi (risankizumab-rzaa) alone could be a viable option for managing your psoriatic arthritis (PsA) and psoriasis. Here are some key points about Skyrizi based on the knowledge base:

- Mechanism of Action: Skyrizi is a biologic therapy that targets IL-23, a protein involved in inflammation, helping to Show Full Answer

Switching to Skyrizi (risankizumab-rzaa) alone could be a viable option for managing your psoriatic arthritis (PsA) and psoriasis. Here are some key points about Skyrizi based on the knowledge base:

- Mechanism of Action: Skyrizi is a biologic therapy that targets IL-23, a protein involved in inflammation, helping to reduce joint pain, stiffness, and swelling.
- Administration: It is administered as a subcutaneous injection every 12 weeks after initial loading doses.
- Efficacy: Clinical trials (KEEPSAKE 1 and 2) showed significant improvement in PsA symptoms, with over half of participants experiencing reduced inflammation and swelling.
- Side Effects: Potential side effects include serious allergic reactions and an increased risk of infections.

Always discuss with your doctor to ensure this switch aligns with your specific health needs.

July 31, 2024

Related content

View All

Dramatic Increase In Symptoms In 30 Days, Humira Not Refrigerated Properly In Shipping? Anyone Experienced This?

A MyPsoriasisTeam Member asked a question 💭
Santa Rosa, CA
March 16

After 10 Yrs Of Natural Treatments To No Avail, My Doctor Thinks It’s Time That I Begin Humira. I’m Terrified. Any Thoughts?

A MyPsoriasisTeam Member asked a question 💭
Stowe, VT
February 13, 2024

Interested To Know What Member Experiences Over Varying Time Periods Have Been With This Methotrexate, As A Systematic Treatment.

A MyPsoriasisTeam Member asked a question 💭
Wellington, NZ
June 10, 2024

FDA’s Approval of Cyltezo, a Biosimilar to Humira, May Mean Lower Psoriasis Treatment Costs
Tried Multiple Psoriasis Treatments? Here’s What To Do Next (VIDEO)
Which Psoriasis Treatment Is Right for Me? (VIDEO)
Already a Member? Log in