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I Need More Information About Skyrizi Injection. I Just Start The Injection Yesterday And I'm A Little Worried Not To Hurt My Immune System

A MyPsoriasisTeam Member asked a question 💭
Silver Spring, MD
April 18, 2024
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A MyPsoriasisTeam Member

Skyrizi (risankizumab-rzaa) is a prescription medication approved for treating moderate to severe plaque psoriasis in adults where systemic therapy or phototherapy is appropriate. Here’s what you need to know about Skyrizi:

- **Administration**: Skyrizi is administered as a subcutaneous injection. After initial loading Show Full Answer

Skyrizi (risankizumab-rzaa) is a prescription medication approved for treating moderate to severe plaque psoriasis in adults where systemic therapy or phototherapy is appropriate. Here’s what you need to know about Skyrizi:

- **Administration**: Skyrizi is administered as a subcutaneous injection. After initial loading doses, it is typically given every 12 weeks.

- **Mechanism**: Skyrizi is a biologic drug that works by inhibiting interleukin-23 (IL-23), a part of the immune system involved in inflammation and autoimmune attacks. By doing so, it helps to prevent the overproduction of IL-23, reducing the symptoms of psoriasis.

- **Common Side Effects**: Some of the common side effects include upper respiratory infections, headaches, fatigue, injection site reactions, and ringworm.

- **Serious Side Effects**: While Skyrizi can be very effective, it also carries the risk of serious side effects such as increased susceptibility to infections, including tuberculosis. It's important to monitor for signs of infection and report them to your healthcare provider.

- **Immune System Concerns**: Like other biologics, Skyrizi can affect the immune system. It specifically targets certain pathways in the immune system to reduce inflammation, which can also make the body more vulnerable to infections.

It's natural to feel a bit worried when starting a new treatment, but many patients find Skyrizi effective for managing their psoriasis while monitoring side effects with their healthcare provider. Always keep your healthcare provider informed about any new symptoms or concerns.

April 18, 2024

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