Yes, some people with long-term psoriasis and psoriatic arthritis (PsA) have experienced difficulties with biologics losing effectiveness over time. Here are some insights from my knowledge base:

- Diminishing Benefits Over Time: Biologics can lose their effectiveness over time. This could be due to the immune system Show Full Answer

Yes, some people with long-term psoriasis and psoriatic arthritis (PsA) have experienced difficulties with biologics losing effectiveness over time. Here are some insights from my knowledge base:

- Diminishing Benefits Over Time: Biologics can lose their effectiveness over time. This could be due to the immune system compensating for the drug, the body consuming the drug faster, or the need for higher doses.
- Switching Biologics: Some people need to switch to another biologic when one stops working. This can be frustrating.
- Personal Experiences: One member mentioned being on Humira for years before it stopped working and then switching to Cosentyx, which also eventually stopped working after three years.

For more detailed personal experiences and professional insights, you can refer to the article "Biologics for Psoriasis" on MyPsoriasisTeam.

 This AI-generated response comes from MyPsoriasisTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Biologics for Psoriasis | MyPsoriasisTeam

My Experience With Biologics for Psoriasis | MyPsoriasisTeam